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Stool Elastase Test

A stool elastase test measures the amount of elastase in your stool to check how well your pancreas is working. Low levels may mean you have exocrine pancreatic insufficiency (EPI), a condition where your pancreas doesn't make enough digestive enzymes.

What this test measures

The test measures the amount of elastase, a digestive enzyme made by the pancreas, in a stool sample.

What your results mean

Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.

Lower-than-normal results

A less than normal amount of elastase may mean you have exocrine pancreatic insufficiency (EPI). Results may be described as moderate or severe pancreatic insufficiency.

Frequently asked questions

What is a stool elastase test?

It measures the amount of elastase in your stool to check if your pancreas is making enough digestive enzymes.

Why is this test done?

It is used to check for exocrine pancreatic insufficiency (EPI) when you have belly pain and other digestive symptoms without a known cause.

What does a low result mean?

A low amount of elastase may mean you have EPI. Your provider will likely order more tests to confirm.

Can a normal result rule out EPI?

No, a normal result does not rule out EPI. You may need other tests if you still have symptoms.

What conditions can cause EPI?

Chronic pancreatitis, cystic fibrosis, pancreatic cancer, Crohn's disease, diabetes, and certain genetic disorders can cause EPI.

Sources

Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.