17-Hydroxyprogesterone Test
This test measures the amount of 17-hydroxyprogesterone (17-OHP) in your blood. It helps diagnose congenital adrenal hyperplasia (CAH), a genetic disorder that affects how your adrenal glands make cortisol.
What this test measures
This test measures the amount of 17-hydroxyprogesterone (17-OHP) in a sample of your blood. 17-OHP is a substance that your adrenal glands make. Normally, your adrenal glands use 17-OHP to make a hormone called cortisol.
What your results mean
Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.
Higher-than-normal results
Higher than normal levels of 17-OHP suggest you or your child probably has CAH. Your provider may order other tests to learn more.
Frequently asked questions
What is 17-hydroxyprogesterone?
17-hydroxyprogesterone (17-OHP) is a substance your adrenal glands make. It is used to produce the hormone cortisol.
Why is this test done?
This test helps diagnose and monitor congenital adrenal hyperplasia (CAH), especially the most common type caused by 21-hydroxylase deficiency.
What does a high result mean?
A high level of 17-OHP usually means you or your child has CAH. Your provider may order more tests to find out more.
What does a normal result mean?
A normal level of 17-OHP means you or your child probably does not have CAH with 21-hydroxylase deficiency.
Can this test be used to monitor treatment?
Yes. If you are being treated for CAH, decreasing levels of 17-OHP over time mean the treatment is working.
Related lab tests
Sources
- MedlinePlus: 17-Hydroxyprogesterone — NIH MedlinePlus
Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.