Mononucleosis (Mono) Tests Test
Mononucleosis (mono) tests help diagnose a mono infection, which is often caused by the Epstein-Barr virus (EBV). The tests look for antibodies in your blood that show up during or after an infection.
What this test measures
Mono tests measure antibodies in the blood that indicate a current or past infection with the Epstein-Barr virus or other viruses that cause mono.
What your results mean
Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.
Higher-than-normal results
A positive test result means EBV antibodies were found in your blood, indicating a current or past infection with the virus that causes mono.
Lower-than-normal results
A negative test result means no EBV antibodies were found, so your symptoms are probably caused by another disorder.
Frequently asked questions
What is the monospot test?
The monospot test looks for specific antibodies in the blood that appear during or after certain infections, including mono.
How long does it take to get monospot results?
Results are usually ready within an hour.
Can the monospot test be wrong?
Yes, the monospot test has a high rate of false negatives, meaning it may show you don't have mono when you actually do.
What does a positive EBV antibody test mean?
A positive EBV antibody test means EBV antibodies were found in your blood, and the types of antibodies can tell if you were infected recently or in the past.
How is mono treated?
There is no cure for mono, but you can relieve symptoms with rest, fluids, lozenges for sore throat, and over-the-counter pain and fever medicines. Antibiotics do not work for mono.
Related lab tests
Sources
- MedlinePlus: Mononucleosis (Mono) Tests — NIH MedlinePlus
Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.