Homocysteine Test Test
A homocysteine test measures the amount of homocysteine in your blood. High levels may indicate a vitamin B deficiency, a genetic disorder, or increased risk for heart disease and stroke.
What this test measures
A homocysteine test measures the amount of homocysteine in a sample of your blood. Homocysteine is an amino acid that your body uses to make proteins.
What your results mean
Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.
Higher-than-normal results
A high homocysteine level may be a sign that you are not getting enough vitamin B12 or folic acid, or that you have homocystinuria. It may also indicate a higher risk of heart disease, stroke, or other blood vessel disorders. Higher levels can also occur with conditions like osteoporosis, chronic kidney disease, hypothyroidism, schizophrenia, or Alzheimer's disease.
Frequently asked questions
What is a homocysteine test?
It measures the amount of homocysteine in your blood. Homocysteine is an amino acid.
Why is homocysteine testing done?
It is used to check for vitamin B6, B12, and folic acid deficiencies, help diagnose homocystinuria, and assess heart attack or stroke risk in people with existing risk factors.
What does a high homocysteine level mean?
It may mean you lack certain B vitamins, have homocystinuria, or have a higher risk of heart disease and stroke.
Can lifestyle affect homocysteine levels?
Yes, smoking, age, and sex can affect levels. Males usually have higher levels, and levels increase with age and after menopause in females.
Is routine homocysteine screening recommended for everyone?
No, routine screening for heart disease risk is not recommended for everyone because it's uncertain how much homocysteine levels affect heart and blood vessel diseases.
Related lab tests
Sources
- MedlinePlus: Homocysteine Test — NIH MedlinePlus
Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.