Hemoglobin Electrophoresis Test
Hemoglobin electrophoresis is a test that measures the different types of hemoglobin in your blood to check for disorders involving abnormal hemoglobin, such as sickle cell disease or thalassemia.
What this test measures
This test measures the levels of different types of hemoglobin in the blood, including normal types (Hgb A, Hgb F) and abnormal types (Hgb S, Hgb C, Hgb E). It helps identify hemoglobin disorders.
What your results mean
Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.
Higher-than-normal results
High levels of certain hemoglobin types may indicate a hemoglobin disorder such as thalassemia or sickle cell disease.
Lower-than-normal results
Low levels of normal hemoglobin types may be a sign of anemia or thalassemia.
Frequently asked questions
What is hemoglobin electrophoresis?
It is a test that measures the different types of hemoglobin in your blood to check for disorders involving abnormal hemoglobin.
What does abnormal hemoglobin mean?
Abnormal hemoglobin can change the size and shape of red blood cells, causing them to clump and block blood flow, leading to anemia and other complications.
What conditions can this test help diagnose?
It helps diagnose sickle cell disease, thalassemia, hemoglobin C disease, and other hemoglobin disorders.
Can a blood transfusion affect my results?
Yes, if you have had a blood transfusion in the last 12 weeks, it can affect your results. Tell your provider.
How are results interpreted?
Your provider will consider your symptoms, medical history, and other blood tests to interpret the results.
Related lab tests
Sources
- MedlinePlus: Hemoglobin Electrophoresis — NIH MedlinePlus
Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.