Globulin Test Test
A globulin test measures proteins in your blood called globulins, which help with liver and kidney function, blood clotting, and fighting infection. It can help diagnose conditions like liver or kidney disease, immune disorders, and certain cancers.
What this test measures
Globulins are a group of proteins in your blood. Some are made by your liver, others by your immune system. Tests include total protein test and serum protein electrophoresis, which measure different types of globulins (alpha, beta, gamma).
What your results mean
Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.
Higher-than-normal results
High globulin levels may be a sign of infection, inflammatory disease, an immune disorder, certain cancers (such as multiple myeloma, Hodgkin lymphoma, or malignant lymphoma), or tuberculosis.
Lower-than-normal results
Low globulin levels may be a sign of liver disease, kidney disease, or malnutrition.
Frequently asked questions
What are globulins?
Globulins are a group of proteins in your blood. Some are made by your liver, others by your immune system. They play an important role in liver and kidney function, blood clotting, and fighting infection.
What do globulin tests measure?
Globulin tests measure the levels of globulins in your blood. There are different types, including alpha, beta, and gamma globulins. Tests include total protein test and serum protein electrophoresis.
Why might I need a globulin test?
Globulin tests can help diagnose liver damage or disease, kidney disease, nutritional problems like malnutrition, certain autoimmune disorders, and certain types of cancer.
What does a low globulin level mean?
Low globulin levels may be a sign of liver disease, kidney disease, or malnutrition.
What does a high globulin level mean?
High globulin levels may be a sign of infection, inflammatory disease, an immune disorder, certain cancers (such as multiple myeloma, Hodgkin lymphoma, or malignant lymphoma), or tuberculosis.
Related lab tests
Sources
- MedlinePlus: Globulin Test — NIH MedlinePlus
Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.