Chymotrypsin in Stool Test
This test measures the amount of chymotrypsin in your stool to check if your pancreas is making enough enzymes to digest food properly.
What this test measures
This test measures the amount of chymotrypsin, an enzyme released by the pancreas to help digest protein, in a stool sample.
What your results mean
Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.
Lower-than-normal results
A low amount of chymotrypsin in stool may mean you have pancreatic insufficiency, but it does not diagnose a specific disorder by itself.
Frequently asked questions
What is chymotrypsin?
Chymotrypsin is an enzyme released by the pancreas that helps break down protein in food during digestion.
Why is this test done?
This test is used to check for pancreatic insufficiency, which can be caused by conditions like chronic pancreatitis and cystic fibrosis.
What does a negative result mean?
A negative result means the amount of chymotrypsin in your stool is below normal, which may indicate pancreatic insufficiency.
What conditions can cause low chymotrypsin?
Low chymotrypsin is most often caused by chronic pancreatitis or cystic fibrosis.
What other tests might be needed?
If your result is negative, your provider may order tests like stool elastase, lipase blood test, or amylase blood test.
Related lab tests
Sources
- MedlinePlus: Chymotrypsin in Stool — NIH MedlinePlus
Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.