Acute Flaccid Myelitis
Also called: AFM
Acute flaccid myelitis (AFM) is a rare but serious neurologic disease that affects the gray matter of the spinal cord, causing muscles and reflexes to become weak. It is sometimes called a "polio-like" illness but is not caused by polioviruses.
Symptoms
- Arm or leg weakness
- Loss of muscle tone and reflexes
- Facial drooping/weakness
- Trouble moving the eyes
- Drooping eyelids
- Trouble swallowing
- Slurred speech
- Pain in the arms, legs, back, or neck
- Respiratory failure (severe)
Causes
AFM can be caused by several different viruses, including enteroviruses, flaviviruses, herpesviruses, and adenoviruses. Most people had a mild respiratory illness or fever before getting AFM.
Diagnosis
Diagnosis may involve a neurologic exam, MRI of the spinal cord and brain, lab tests on cerebrospinal fluid, and nerve conduction/EMG studies. Tests should be done as soon as possible after symptoms start.
Treatment
There is no specific treatment for AFM. A neurologist may recommend treatments for specific symptoms.
Lifestyle
- Physical therapy
- Occupational therapy
When to see a doctor
If you or your child develops any symptoms of AFM, get medical care right away.
Frequently asked questions
What is acute flaccid myelitis (AFM)?
AFM is a rare but serious neurologic disease that affects the spinal cord, causing muscle weakness.
What causes AFM?
AFM can be caused by several viruses, including enteroviruses, flaviviruses, herpesviruses, and adenoviruses.
Who is most likely to get AFM?
Anyone can get AFM, but most cases (over 90%) have been in young children.
What are the symptoms of AFM?
Symptoms include sudden arm or leg weakness, loss of muscle tone and reflexes, and sometimes facial drooping, trouble swallowing, or breathing problems.
How is AFM treated?
There is no specific treatment for AFM. A neurologist may recommend physical or occupational therapy for symptoms.
Related conditions
Sources
- MedlinePlus: Acute Flaccid Myelitis — NIH MedlinePlus
- West Nile virus: epidemiology, prevention, clinical features, diagnosis, treatment, and open research questions. — Ann Med, 2026
- Progress in enterovirus D68-neutralizing antibodies and vaccines. — J Virol, 2026
- Complexities in evaluation and management of infectious myelopathies. — Curr Opin Infect Dis, 2026
- [Acute Flaccid Myelitis]. — Brain Nerve, 2026
- Enterovirus D68 and Acute Neurologic Outcomes: A Systematic Review and Meta-Analysis (2010-2025). — Rev Med Virol, 2026
Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.